Ethical Implications: Pain, Coma, and Related Disorders
نویسنده
چکیده
Introduction of drugs (colloquially known as painkillers) used to relieve pain (achieve analgesia). Analgesic drugs act in various ways on the peripheral and central nervous systems; they include paracetamol (acetaminophen), the nonsteroidal anti-inflammatory drugs (NSAIDs) such as the salicylates, narcotic drugs such as morphine, synthetic drugs with narcotic properties such as tramadol, and various others. Functional neuroimaging – The use of neuroimaging technology to measure an aspect of brain function, often with a view to understanding the relationship between activity in certain brain areas and specific mental functions. Hydranencephaly – A type of cephalic disorder. This is a rare condition in which the cerebral hemispheres are absent and replaced by sacs filled with cerebrospinal fluid. Opiates – Named so because they are constituents or derivatives of constituents found in opium. The major biologically active opiates found in opium are morphine, codeine, thebaine, and papaverine. Pain – Defined as an unpleasant sensory and emotional experience associated with real or potential tissue damage. Primary somatosensory area – In the human cortex it is located in the postcentral gyrus (parietal lobe). It is the location of the primary somatosensory cortex, the main sensory receptive area for the sense of touch. Sedative – A substance that depresses the central nervous system, resulting in calmness, relaxation, reduction of anxiety,
منابع مشابه
Ethics in Disorders of Consciousness
The introduction of the mechanical ventilator in the 1950s and the development of intensive care in the 1960s permitted many patients to sustain their vegetative functions and survive severe injuries. Despite such advances, in many cases patients were found to suffer from altered states of consciousness which had never been encountered before as these patients would normally have died from apne...
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Detecting pain in severely brain-injured patients recovering from coma represents a real challenge. Patients with disorders of consciousness are unable to consistently or reliably communicate their feelings and potential perception of pain. However, recent studies suggest that patients in a minimally conscious state can experience pain to some extent. Pain monitoring in these patients is hence ...
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Brain damage of various aetiologies can lead to different disorders of consciousness (DOC), varying from coma to vegetative, to minimally conscious states. Each state is characterised by a different degree of wakefulness, awareness, pain sensitivity and is differentially handled with respect to treatment, ethical considerations and end-oflife decisions. Thus, its correct identification is cruci...
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BACKGROUND The Nociception Coma Scale-Revised (NCS-R) was recently validated to assess possible pain perception in patients with disorders of consciousness. OBJECTIVE To identify correlations between cerebral glucose metabolism and NCS-R total scores. METHODS [18F]-fluorodeoxyglucose positron emission tomography, NCS-R, and Coma Recovery Scale-Revised assessments were performed in 49 patien...
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Chronic disorders of consciousness Chronic disorders of consciousness (CDC) are states of illness that are notorious for provoking substantial ethical quandaries. The fiction literature, cinema and theater abound with stories of individuals who have been lying in coma for months or years until they eventually (and miraculously) wake up to see a world that has significantly changed. Famous examp...
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